Design of macroscopic objects using 3D printing to release an active molecule

The aim of this work is to design macroscopic objects that enable the release of an ‘active’ molecule encapsulated in an edible, absorbable matrix, in a quantity and at a rate adapted to the user. In particular, the aim is to develop compositions based on a model thermoplastic biopolymer, zein, a corn reserve protein, and to characterise their thermomechanical and rheological properties in relation to the shaping process and the content of active principle-plasticizer (e.g. ionic liquid of therapeutic interest).

The macroscopic shape and cellular structure of the object are designed using numerical approaches and produced using the 3D printing process by direct extrusion-deposition of molten wire.

This research will provide a better understanding of the mechanisms linking structure at different scales and the release of biopolymer/active molecule systems. Applications are mainly in the agri-food, pharmaceutical and biomedical sectors.