Some results

Increased exposure of the population to hemp seed has already revealed allergies, with symptoms ranging from isolated skin manifestations to anaphylaxis. These allergies can occur in patients who are already allergic to another food, in what is known as a cross-reaction.

During pregnancy, the mother's diet modifies the intestinal microbiota and can therefore have an impact on the immune system of the foetus in utero by modifying the transfer of immune factors, microbes and bacterial metabolites mediated by the umbilical cord, placenta and amniotic fluid. Prebiotics are fibres that act as fermentable substrates for specific bacteria, leading to the release of metabolites, or by exerting direct effects on immune cells. We hypothesised that prebiotic supplementation during pregnancy could modify the maternal microbiota towards a higher production of metabolites and favour a healthy immune imprint in the foetus.

Chemical modification by deamidation or enzymatic hydrolysis of gluten proteins influences their interaction with immune cells

Some children allergic to eggs can still eat them in cookies. How can we recognize these children?

Using a murine animal model, this work showed that induction of food allergy to wheat gluten aggravated the symptoms of house dust mite asthma subsequently induced in mice.

A chimeric IgE (mouse/man) specific for deamidated sequences has been developed and its ability to classify the allergenicity of deamidated glutens has been demonstrated.